Our approacH
STEM3: The first integrated, systems-level oncology solution
STEM3: System for Tumor Ecosystem Modulation
01
map
Explore the broader tumor landscape and potential druggable matrix targets using:
- Multi-modal human tissue data
- Matrix biology
- Phenomics
02
MODEL
Create proprietary cancer type-specific ecosystem models to discover novel biology
- Unique AI/ML models incorporating data from across the ecosystem
- Validate with gold-standard in vivo models
03
MODULATE
Rapidly (in days) compare genetic and compound phenotypes to identify compound starting points:
- Improved drug candidates
- Better clinical-stage results
- Improved patient outcomes
Data Feed back into our matrix map
Our approacH
Our STEM3 platform is an integrated, system-level solution: System for Tumor Ecosystem Mapping/Modeling/Modulation
Seek triple-threat protein targets (cancer cells | matrix | immune cells) & find drugs to attack them
01
map
THE ECOSYSTEM
THE ECOSYSTEM
schematic; Map currently at MVP stage
02
MODEL
THE ECOSYSTEM
THE ECOSYSTEM
in use for sarcoma
03
MODULATE
THE ECOSYSTEM
THE ECOSYSTEM
in use for sarcoma
in use for sarcoma
schematic; Map currently at MVP stage
in use for sarcoma
DATA FEEDS BACK INTO OUR MAP
We identify protein targets that simultaneously control:
Cancer cell growth
Immune cell function
Tumor Matrix Architecture
Inhibiting triple-threat targets will revolutionize cancer therapy
